Don Rickles, best known as being perhaps the best insult comic of all time, has passed away. He was 90.

The comedienne died Thursday from kidney failure at his Los Angeles home, according to his publicist Paul Shefrin.

In a 1965 appearance on "The Tonight Show" with Johnny Carson gave him his national breakthrough and he quickly became a regular guest. But it was "The Dean Martin Celebrity Roast," which ran from 1974 to 1984 on NBC, where Rickles' barbs and zingers helped to firmly establish him as "Mr. Warmth."